Description
Recombinant full-length human METTL3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_019852.
N6-adenosine-methyltransferase 70kDa subunit (MT-A70 or METTL3) belongs to the methyltransferase superfamily that methylates adenosine residues of some RNAs. It acts as a regulator of the circadian clock, differentiation of embryonic stem cells and primary miRNA processing